Metabolomics across scales: from single cells to population studies

Johnson, C. H., Ivanisevic, J. & Siuzdak, G. Metabolomics: beyond biomarkers and towards mechanisms. Nat. Rev. Mol. Cell Biol. 17, 451–459 (2016). Article  CAS  PubMed  PubMed Central  Google Scholar  Wellen, K. E. & Thompson, C. B. A two-way street: reciprocal regulation of metabolism and signalling. Nat. Rev. Mol. Cell Biol. 13, 270–276 (2012). Article  CAS …

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‘Super Mario Galaxy Movie’ Is Year’s Highest Grossing Movie, ‘Project Hail Mary’ Hits $500 Million

“The Super Mario Galaxy Movie” is officially the year’s highest-grossing film to date with $629 million at the global box office. While the film’s towering ticket sales will continue climb and climb (likely toward the $1 billion mark in the coming weeks), it’ll contend with major upcoming tentpoles like “Spider-Man: Brand New Day,” Christopher Nolan’s…

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Multiomics and deep learning dissect regulatory syntax in human development

Ethics statement De-identified tissue samples were collected at Stanford University School of Medicine from elective termination of pregnancy procedures with informed consent for the research use of tissues in observance of relevant legal and institutional ethical regulations. No demographic information was collected. Consent was obtained by the medical team. The relevant tissue sample processing and…

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