Non-invasive profiling of the tumour microenvironment with spatial ecotypes

Human subjects All human samples included in this study were collected with informed consent for research use and received approval from the Institutional Review Boards of Yale University School of Medicine and Washington University School of Medicine, in accordance with the principles of the Declaration of Helsinki (2013). These samples, obtained from a total of…

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the mysterious ‘dark’ proteins that might play a big role in biology

Some proteins (artist’s illustration) are being reclassified in databases as a result of the latest findings.Credit: Christoph Burgstedt/Getty The human genome contains around 20,000 genes that hold instructions for making working proteins, as most genetic databases now indicate. However, some scientists say there might be thousands more ‘dark proteins’ with unknown but potentially important roles…

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