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Personalized CRISPR therapies could soon reach thousands — here’s how

In February, the US Food and Drug Administration (FDA) proposed a radical rethink of how scientists, physicians and manufacturers develop personalized genetic therapies. The regulator’s suggested introduction of a ‘plausible mechanism pathway’ should increase incentives for drug companies to develop personalized treatments, including gene-editing therapies for rare disorders (see go.nature.com/4mnmgzq). The baby whose life was…

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Gabriel Byrne and Geraldine James to Star in ’45 Years’ Stage Premiere

Gabriel Byrne and Geraldine James will lead the world stage premiere of “45 Years,” Hannah Patterson’s theatrical adaptation of Andrew Haigh’s 2015 film, directed by Prasanna Puwanarajah, at the Minerva Theatre, Chichester, U.K., from June 12 to July 11. The story centres on a couple in the days before their anniversary celebrations, whose relationship is…

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