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Linear RAG scanning mediates editing of Igκ variable region repertoires

Experimental procedures We did not use statistical methods to predetermine sample size. We also did not randomize experiments. During experiments and outcome assessments, investigators were not blinded to allocation. Mice We purchased wild-type 129SV mice from Taconic Biosciences. We have previously described the generation and characterization of 129SV mice harbouring the Cer/Sis deletion22. Mouse work…

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What is China’s role in the Iran war?

As the number one importer of Iranian oil, China has a major problem with any constriction of exports in the Gulf – including the US blockade of Iran’s ports, which began on Monday. Beijing has condemned the US blockade, calling it “irresponsible and dangerous”. It has also reportedly sought to play peacemaker in the conflict,…

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