Early fibrotic niches establish tumour-permissive microenvironments

Mice Sftpc–CreERT2 (028054), R26R–Confetti (013731), Pdgfrα–CreERT2 (032770), R26R–iDTR (007900), NOD/Scid Il2rg null Tg (NSG: 005557) and Ai6/RCL–ZsGreen (007906) animals were obtained from The Jackson Laboratory. AregloxP/loxP animals were kindly provided by M. Clatworthy from the University of Cambridge. Red2Kras mice were generated in-house as previously described22. CCR2–CreERT2 mice were kindly provided by B. Becher (University…

Read More

Collins, Sullivan break with Senate GOP leaders on amendment to reverse SNAP cuts

Senate Republicans on Wednesday defeated an amendment sponsored by Sen. Ben Ray Luján (D-N.M.) to create a reserve fund to lower grocery costs and reverse an estimated $187 billion in cuts to the Supplemental Nutrition Assistance Program enacted by last year’s One Big Beautiful Bill Act. Two vulnerable Republican senators — Sens. Susan Collins (R-Maine)……

Read More

Mechanically driven Li dendrite penetration in garnet solid electrolyte

Li dendrite growth in solid electrolytes LLZTO solid electrolytes were obtained from Toshima Manufacturing Co., Ltd. The pellets were mechanically ground to a thickness of approximately 150 μm, with final polishing performed using a 0.05-μm alcohol-based colloidal silica suspension. To reduce the interfacial resistance between lithium and the solid electrolyte, the thin LLZTO discs were immersed…

Read More