Template-driven scaffolding of SCFFBXO42 regulates PP2A degradation

Cancer dependency map analysis Genome-wide gene dependency scores were obtained from the Cancer Dependency Map (DepMap) 2024 Q2 CRISPRGeneEffect.csv public data release47. Cell line generation, exogenous expression, siRNA and cell viability assays Cell lines were grown in RPMI 1640 medium supplemented with 10% FCS with the exception of HEK293T cells, which were grown in Dulbecco’s…

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