Netrin1 blockade alleviates resistance to chemotherapy in pancreatic cancer

Lap-NET1 clinical trial Study design and participants Lap-NET1 is a multicentric, prospective, single-arm phase 1b trial. This study included a safety lead-in phase to confirm the recommended dose of NP137 in combination with mFOLFIRINOX (ClinicalTrials.gov identifier: NCT05546853). Patients were enrolled and treated between March 2023 and June 2024 at nine sites in France. Eligible patients…

Read More

    Optimistic About Private Credit Opportunities: Poli

    Danielle Poli, co-portfolio manager, global credit at Oaktree Capital, and Gretchen Lam, CEO of Octagon Credit Investors, join Scarlet Fu on “Bloomberg Deals.” The titans of private markets descended on Beverly Hills for the annual Milken Institute, where they made it clear they were ready to move on from private credit’s recent woes. (Source: Bloomberg)…

    Read More