Steric hindrance of antibody binding in an Omicron spike fusion intermediate

Low, J. S. et al. ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies. Science 377, 735–741 (2022). Article  ADS  CAS  PubMed  PubMed Central  Google Scholar  Sun, X. et al. Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nat. Microbiol. 7, 1063–1074 (2022). Article  CAS  PubMed  Google Scholar  Qu, P….

Read More

The ‘crazy rule-defying’ genes that determine sex

Sex, Genes and Chromosomes: Their Discovery, Function and Evolution Jennifer A. Marshall Graves Cambridge Univ. Press (2026) “Sex is the most profound normal difference between human individuals,” explains geneticist Jennifer Graves in Sex, Genes and Chromosomes. In this definitive and wide-ranging book, she outlines the discovery, molecular biology and evolution of sex chromosomes as well…

Read More

THORChain Opens Refund Portal After $10M Hack

THORChain has confirmed a $10 million exploit and launched a recovery portal, giving affected users a self-custodial path to revoke malicious token approvals and submit refund claims backed by a treasury-provisioned refund pool of equal size. In a Saturday post on X, THORChain Foundation introduced the recovery portal, saying that “affected users are now able…

Read More