Nature, Published online: 16 April 2026; doi:10.1038/d41586-026-01210-7 Most of the individuals in a seventeenth-century-Switzerland burial site had performed strenuous manual labour and died before the age of 20. Source link
Nature, Published online: 16 April 2026; doi:10.1038/d41586-026-01213-4 Study of gene expression also finds age-related increases in men’s vulnerability to certain cancers. Source link
The winner of the Q4Bio US$2 million prize used the IBM Quantum System One computer, which is housed in the Cleveland Clinic, to do simulations.Credit: Ryan Lavine for IBM A team developing light-sensitive cancer drugs has won a US$2-million Quantum for Bio (Q4Bio) prize for demonstrating a potential use for quantum computers in health care….
The nine-to-five PhD is an ever-elusive goal: many candidates aspire to it but few end up achieving such an impressive work–life balance. Nature’s 2025 global PhD survey found that 50% of respondents, who were self-selecting, identified a culture of long work hours at their university. This fuels dissatisfaction, and those who spent more than 60…
Given that there are many emerging targets in the efforts to treat cancer, precision medicine is in the spotlight. Many DNA changes — such as mutations, changes in the number of copies of a gene or fusions of genes — can drive cancer-cell growth and proliferation, and can affect sensitivity or resistance to selected therapies….
Experimental setup: distillation on an unrelated domain This section describes the structure of our main experiments (Fig. 2). We start with a reference model, such as GPT-4.1 (ref. 45). Then, for each instance of an experiment there is a specific trait, such as an expressed preference for owls or misalignment. Moreover, we have the following: 1….
Mice All procedures were approved by the New York University Langone Medical Center Institutional Animal Care and Use Committee in compliance with the US National Institutes of Health Guidelines for the Care and Use of Laboratory Animals. Adult mice 12–38 weeks old were used for all of the studies. Mice were housed at 18–23 °C with 40–60% humidity under…
You have full access to this article via your institution. Hello Nature readers, would you like to get this Briefing in your inbox free every day? Sign up here. To capture images of birds, such as this yellow-rumped warbler (Setophaga coronata), flying at night, one research-team member detected the thermal signature of the bird and…
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-01187-3 A high-resolution atlas of the healthy human liver has been assembled using gene-expression profiling and spatial mapping of cells in samples from living donors. The atlas reveals human-specific patterns of gene expression in different zones and uncovers spatially resolved adaptations in liver cells from individuals with the disease…
Mammalian oocytes store proteins for embryonic development on abundant structures known as cytoplasmic lattices (CPLs)1; however, the mechanisms by which they achieve this are unclear, largely because the molecular composition of the lattices themselves is unknown. Here, we use cryo-electron microscopy and artificial intelligence-based modeling to elucidate the molecular architecture and protein composition of native…