CAR-T therapy vanquishes ultra-rare disease trio

Antibodies (three-lobed structures, artist’s impression) that attack a person’s own tissues can lead to autoimmune disease.Credit: Ruslanas Baranauskas/SPL A woman with an ultra-rare combination of three autoimmune diseases has had no symptoms since receiving a single dose of engineered immune cells, doctors in Germany report today1. She had previously received nine other types of treatment…

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Should academic misconduct be catalogued? Proposed US database sparks debate

Research misconduct can include a variety of infractions, including data fraud and manipulation.Credit: Tom Werner/Getty For decades, academic institutions have struggled with how to prevent researchers who have committed misconduct from securing jobs at new universities while hiding the bad behaviour. A proposal published today in the journal Science1 offers a solution, at least in…

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Author Correction: Multi-omic profiling reveals age-related immune dynamics in healthy adults

These authors contributed equally: Qiuyu Gong, Mehul Sharma Allen Institute for Immunology, Seattle, WA, USA Qiuyu Gong, Mehul Sharma, Marla C. Glass, Emma L. Kuan, Aishwarya Chander, Mansi Singh, Lucas T. Graybuck, Zachary J. Thomson, Christian M. LaFrance, Samir Rachid Zaim, Tao Peng, Lauren Y. Okada, Palak C. Genge, Katherine E. Henderson, Elisabeth M. Dornisch, Erik D. Layton, Peter J. Wittig, Alexander T. Heubeck, Nelson M. Mukuka, Julian Reading, Garrett Strawn, Teminijesu Titus-Adewunmi, Kathleen Abadie, Charles R. Roll, Veronica…

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balancing two experiments at once

After reflecting on how the mid-career and midlife stages interact, Yu Tao developed several habits that he practises as a mid-career researcher.Credit: Benjamin Smith One afternoon in November last year, two e-mails landed in my inbox minutes apart. The first was from my son’s school, reminding parents that the transition to secondary education would begin…

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