Glycerol-driven TNAP activation in thermogenesis and mineralization

Millan, J. L. Alkaline phosphatases: structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes. Purinergic Signal. 2, 335–341 (2006). Article  CAS  PubMed  PubMed Central  Google Scholar  Rahbani, J. F. et al. ADRA1A–Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP. Nat. Metab. 4, 1459–1473 (2022). Article  CAS  PubMed  PubMed…

Read More

Live updates: Senate plans for vote-a-rama; California gubernatorial candidates prepare for debate

The Senate is expected to hold a vote-a-rama Wednesday night on the budget resolution that will serve as a blueprint for the GOP-only bill they aim to use to fund immigration enforcement. That GOP-only bill, which Republicans hope to pass through the budget reconciliation process that bypasses the Democratic filibuster, is part of a two-step……

Read More

Electronic origin of reorganization energy in interfacial electron transfer

Chemicals and materials Natural Kish graphite crystals (Grade 300, 99.99% purity) were procured from Graphene Supermarket. Hexagonal boron nitride crystals were provided by T. Taniguchi and K. Watanabe, and were used as received. Large, flat crystals of RuCl3 were grown by chemical vapour transport following the procedure detailed in a previous study41. Briefly, commercial RuCl3…

Read More