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Scarcity shapes nearly every aspect of health-care delivery in low- and middle-income countries (LMICs), so making good decisions about how to allocate resources is crucial. Yet the tools used to guide these choices are themselves scarce. Methods for forecasting demand, coordinating supply chains and distributing resources, which are taken for granted in high-income settings, are…
Animals The animal work was approved by the Emory University Institutional Animal Care and Use Committee (IACUC) under protocol 202100136. Twelve adult Indian-origin rhesus macaques (Macaca mulatta) (RM) were housed at the Emory National Primate Research Center (ENPRC) and maintained in accordance with NIH guidelines. Animal care facilities are accredited by the US Department of…
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T cells, shown here attacking a tumour cell, might provide a better defence after a person has eaten.Credit: selvanegra/Getty The best time to get an infection might be after a meal, suggest experiments in mice and humans that found that certain immune cells, known as T cells, seem to get a boost from food. The…
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Nature, Published online: 29 April 2026; doi:10.1038/d41586-026-01406-x Eating a meal could lead to T cells springing into action more quickly— plus, 40 years after Chornobyl, how future nuclear calamities can be avoided. Source link
Arenes and alkenes share the presence of C(sp2)–H bonds of similar bond dissociation energy, yet their reactivity differs fundamentally. Arenes undergo electrophilic substitution because of aromatic stabilization, for example, in Friedel–Crafts alkylation. By contrast, alkenes react by electrophilic addition (Fig. 1a), which prevents analogous substitution chemistry, so there is no alkene analogue to Friedel–Crafts alkylation,…